The human body is a unique machinery with a complex network of tiny blood vessels. The resulting orchestrated circulation, however, may be disrupted in cardiovascular ailments and cancer. While modern technology permits drugs to target specific diseased sites, Prof. Chakraborty’s lecture will share insights on how we can test accurately for efficacy of such therapeutics. He will address how animal testing prior to human trials may not yield accurate results due to differences in physiology. He will talk about the possibility of bioengineering the human microvascular environment and how this could be achieved without sophisticated and costly infrastructure.
What if the human microvascular environment could be bioengineered? Does this sound more like science fiction than fact?
Infosys Prize laureate Prof. Suman Chakraborty throws light on his work in creating a new technology to engineer a microvascular network on a chip mimicking human physiology, using a frugal approach that does not demand sophisticated fabrication facilities. He demonstrates how this development helps in understanding how the deformation of these tiny capillaries may influence the magnetic-targeting of drug-loaded nanoparticles towards specific diseased sites.